Description We are recruiting a Junior Specialist to facilitate the establishment of a new research lab in the Department of Cell and Tissue Biology. We study how RNA chaperones affect human gene expression in normal cells, cancers, and developmental disorders. We have a variety of projects including how RNA chaperones influence cancer formation, how RNA moves around in the crowded cytoplasm of cells, and connecting the molecular level function of RNA chaperones to their cellular phenotypes. The Junior Specialist will be foundational to the lab as one of its first members and contribute to any or all of these projects. The specific role(s) of the Junior Specialist will include optimizing existing protocols as they are transferred to a new lab environment, establishing cell culture experiments, genome engineering of transformed and stem cell lines using CRISPR/Cas9, assisting in ordering lab equipment and supplies, and assisting in setting up new equipment. Experience in the Floor lab will prepare the candidate for future work in molecular & cell biology including in vitro disease modeling, genome editing, high-throughput sequencing, RNA biology, and other research areas. This position is ideal for those looking for more hands-on research experience after finishing college. A minimum of a one year commitment is required although a two year commitment is preferred.
Required Qualifications • BA/BS degree may be in process at the time of application submission, however, the degree must be possessed by the appointment effective date. • One or more years of recent, directly related laboratory work experience utilizing techniques or methods required by the position. • Experience with general laboratory techniques, especially basic molecular and cellular biology techniques (including but not limited to DNA and RNA isolation, PCR, gel electrophoresis, DNA assembly, bacterial transformation, mammalian cell culture, etc.). • Excellent organizational and interpersonal communication skills (verbal and written). • Willingness and ability to learn new methods and skills for changing research priorities. • Ability to work independently and as a member of a research team. • Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Preferred Qualifications • Prior experience with mammalian tissue culture especially of human stem cells • Prior experience in the design and assembly of DNA constructs (via restriction digestion and ligation, Gibson assemblies, Golden-Gate assemblies, etc.).
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.