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Life Science Research Professional 1

Stanford University

Details

Posted: 11-Dec-22

Location: Stanford, California

Type: Full-time

Salary: Open

Internal Number: 97282

Life Science Research Professional 1

What makes us human? The Fraser Lab in the Department of Biology at Stanford University is seeking a Basic Life Science Research Professional 1 (undergraduate or masters-level) to help us answer this question. We use human-chimpanzee "hybrid" induced pluripotent stem cells and cutting-edge CRISPR-based tools to understand the genetics behind uniquely human traits such as our bigger brains and much higher risk for Alzheimer's disease and schizophrenia. Previous work using these hybrid stem cells-- a novel platform recently developed in our lab-- showed that a change in the expression of a single gene is responsible for our unique facial structure and introduced human-chimpanzee hybrid brain organoids as a powerful model for studying the evolution of the human brain (see https://rdcu.be/c0Pj5 and https://rdcu.be/c0Pka for the publications).

In the lab, you will work closely with other lab members as well as the principal investigator and be heavily involved in the planning, execution, and publication of exciting science. In general, the day-to-day work in the position will focus on the construction and validation of plasmids used to alter the expression of human and chimpanzee genes using CRISPR and the generation of libraries for RNA sequencing. In addition, there will be the opportunity to learn and apply powerful techniques such as stem cell culture and differentiation. A small amount of time will be devoted to lab organization/safety. Overall, this is an excellent opportunity for anyone with an undergraduate or masters degree and previous experience with molecular biology techniques. Familiarity with mammalian stem cell culture or CRISPR-based approaches is a plus but is not required.

Past Research Professionals in the lab have published first-author papers in top journals like Cell and have gone on to PhD programs at Stanford as well as exciting positions in industry. We are fully committed to helping all lab members accomplish their professional goals by developing skills sought after in both academia and industry, providing recommendation letters, and helping to craft compelling applications. We especially encourage people from backgrounds historically underrepresented in science to apply. We hope you'll join us to help discover the answers to age-old questions about what makes us human.

This is a one-year fixed-term position with a possible renewal.

Note: The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

CORE DUTIES:

Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
Independently conduct experiments; maintain detailed records of experiments and outcomes.
Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
Assist with orientation and training of new staff or students on lab procedures or techniques.

MINIMUM REQUIREMENTS:

Education & Experience:

Bachelor's degree in related scientific field.

Knowledge, Skills and Abilities:

General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
Ability to maintain detailed records of experiments and outcomes.
General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
Ability to work under deadlines with general guidance.
Excellent organizational skills and demonstrated ability to accurately complete detailed work.

Certifications and Licenses:

None

PHYSICAL REQUIREMENTS*:

Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
Must have correctible vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
Ability to lift heavy objects weighing up to 50 pounds.
Ability to work in a dusty, dirty, and odorous environment.
Position may require repetitive motion.

* - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of the job.

WORKING CONDITIONS:

May require working in close proximity to blood borne pathogens.
May require work in an environment where animals are used for teaching and research.
Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and business needs.

WORK STANDARDS:

Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned.
Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.

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About Stanford University

Why work at Stanford?Stanford University has changed the world, over and over again.We are one of Silicon Valley's largest employers - and also one of the most unique. Our mission is to educate future leaders and promote interdisciplinary, world-class research and teaching. This passion makes Stanford an intensely creative, rewarding, and challenging place to work. At the same time, our traditions of respect and collaboration sustain a humane, supportive environment in which to pursue your life and your career.At Stanford you'll work with bright, diverse, dedicated people. You'll find encouragement to learn and grow. You'll enjoy excellent benefits and an outstanding environment. How will it change you?

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