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Application
Details
Posted: 11-Mar-23
Location: Pasadena, California
Type: Full-time
Salary: Open
Internal Number: 3996161
Caltech
Exempt Overtime Eligible: Overtime Eligible
Benefits Eligible: Benefit Based
Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.
Job Summary
The Hay lab is interested in a variety of topics. Many projects can be thought of as involving, in some sense, study of, and/or engineering the composition or fate of populations. At the subcellular level, we are interested in mitochondrial genomes, why mutant versions accumulate, how quality control occurs to eliminate defective mitochondrial genomes, why quality control often fails (during aging), and the development of methods for enhancing it. At the level of the cell, we are interested in cell death and neurodegeneration. At the level of individual organisms, we are interested in methods for inducing long-term infertility using gene therapy. At the level of populations of organisms, we are interested in developing technologies for modifying the genetic composition or fate of wild populations, ranging from prokaryotes to plants, insects and mammals using gene drive.
Common activities the successful candidate may contribute to include recombinant DNA cloning, the creation of transgenic organisms, cell culture, Drosophila genetics, plant (Arabidopsis) genetics, RNA and DNA sequencing, qPCR, mouse husbandry and reproductive biology, and immunofluorescence microscopy. Primary work will be with others but may also involve independent research. Publications outlining these interests can be found at our website below.
https://www.haylab.caltech.edu
Essential Job Duties
- Perform synthesis and cloning of multi-part constructs for use in cell culture and transgenesis.
- Perform Drosophila or plant genetics experiments using transgenic organisms and mutants.
- Perform qPCR and other forms of quantitative analysis of mitochondrial DNA of various genotypes.
- Perform cell culture experiments using transient and stably transfected cells. Cell culture experiments may include immunostaining, imaging, qPCR, mRNA transfections.
- Mouse husbandry and reproduction assays
- Keep detailed records of experimental research.
- Other laboratory duties such as ordering as assigned.
Basic Qualifications
- Bachelor's degree in biology, biochemistry, chemistry, physics, bioengineering or related field.
- Some experience in molecular biology and/or genetics.
- Able to work independently and as a part of a team.
- Able to organize your own time and effort across multiple projects.
- Excellent attention to detail, documentation, and organizational skills.
Preferred Qualifications
- Some prior work experience as a lab technician or equivalent work experience.
- Some experience with molecular techniques, genetics, cell culture, biochemistry, or other biological research activities.
Required Documents
- Resume
To be considered for this position please visit our web site and apply on line at the following link: https://hr.caltech.edu/work/job_openings
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
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The California Institute of Technology (Caltech) is a world-renowned science and engineering research and education institution, where extraordinary faculty and students seek answers to complex questions, discover new knowledge, lead innovation, and transform our future.
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