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Associate Specialist - Jura Lab

University of California San Francisco

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Details

Posted: 15-Nov-23

Location: San Francisco, California

Type: Full-time

Salary: Open

Internal Number: JPF04821

Associate Specialist - Jura Lab

The Jura Lab in the Cardiovascular Research Institute is now recruiting an Associate Specialist. The responsibilities will include design and execution of an independent research project focused on the area of receptor tyrosine kinase signaling, and intra-domain allosteric regulation of receptor tyrosine kinase activity. Various protein expression constructs will be designed and screened for expression and purification from various sources (insect and mammalian cells). Purified protein will be subject to enzymatic analysis in the in vitro kinase assays, and structural analysis by cryo-electron microscopy. In addition, cell-based signaling assays will be conducted to test structural models generated throughout the course of the research project. Other responsibilities will include training and mentoring junior trainees in the lab recruited to work on related projects.

Required Qualifications:

• Specialists appointed at the Associate rank must possess a master's degree (or equivalent degree) or five to ten years of experience in the relevant specialization.
• At least 3 years' experience performing the following experiments: molecular cloning and cDNA mutagenesis; protein expression, purification and biophysical characterization using multi-angle light scattering (MALS) and hydrogen-deuterium mass spectrometry (HDX-MS); structural analysis using X-ray crystallography and cryo-electron microscopy (cryo-EM); and tissue culture, including cell culture maintenance in BSL2 facility, cell transfection using liposome and lentiviral-based methods, Western blot and flow cytometry.

Preferred Qualifications:

• Post-graduate training in field.

Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $70,500 - $82,100.

Please apply online at https://aprecruit.ucsf.edu/JPF04821.

Document requirements

• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).

• Cover Letter (Optional)

• Statement of Research

• Statement of Teaching (Optional)

• Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity Statement
  (Optional)

• Misc / Additional (Optional)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

San Francisco, CA

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About University of California San Francisco

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.

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