Specialist - Structural Biology and Biochemistry (Verba Lab)

Multiple specialist positions are available immediately in the Verba laboratory at the Mission Bay Campus of UCSF. Verba lab (https://cmp.ucsf.edu/faculty/kliment-verba) seeks to understand the molecular fundamentals of how cells make decisions and how these processes are hijacked by disease and pathogens. To this end we use and develop variety of biochemical and structural techniques including x-ray crystallography and cryo-EM. You will learn and apply these methods to help develop inhibitors against SARS CoV2 and other viruses with a pandemic potential. The candidate will design constructs for recombinant protein expression, express and purify viral proteins. The candidate will obtain molecular structures of viral proteins and will work closely with medicinal chemistry group to guide inhibitor design and optimization. This is a multi-lab effort (https://qcrg.ucsf.edu/qcrg-avidd-overview) and is an incredible opportunity to get exposed to the different ways of thinking and methodologies which are required to go from basic science discovery to an effective small molecule antiviral.
An ideal candidate is highly motivated, excited to learn, independent, curiosity driven, creative and has excellent interpersonal skills.

Requirements

• Junior Specialist: Bachelors of Science degree with biology wet lab experience
• Assistant Specialist: Either a Master's degree or a Bachelor's degree with three or more years of research experience.
• Associate Specialist: Master's degree or five to ten years of research experience in biological sciences or an appropriate scientific field in addition to a record of academic accomplishments including contributions to published or in press research in the field and a demonstrated record of University and/or public service.
• Full Specialist- terminal degree (or equivalent degree) or ten or more years of research experience in biological sciences or an appropriate scientific field in addition to a record of academic accomplishments including contributions to published or in press research in the field and a demonstrated record of University and/or public service.
• Hands on wet lab molecular biology/biochemistry experience.
• Able to work independently and meet deadlines; recognize and resolve problems while maintaining high level of organization.
• Able to keep experimental records
• Effective verbal and written communication skills
• Experience in Microsoft Office or its equivalent
• Ability and desire to learn new experimental approaches
• Candidate must meet the required qualifications at the time of appointment.
• Candidate's CV must state required qualifications (or if pending) upon submission.

Preferred Qualifications

• Experience with structural biology techniques (cryo-EM and/or X-ray crystallography and/or NMR)
• Proficiency in protein expression and purification from bacterial or eukaryotic expression systems
• Programming experience

Please apply online at https://aprecruit.ucsf.edu/JPF05415 , with a CV, cover letter, and three references.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100-$188,200.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.
* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
* UC Sexual Violence and Sexual Harassment Policy: https://policy.ucop.edu/doc/4000385/SVSH
* UC Anti-Discrimination Policy for Employees, Students and Third Parties: https://policy.ucop.edu/doc/1001004/Anti-Discrimination
* APM - 035: Affirmative Action and Nondiscrimination in Employment: https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf